Postdoc (m/f/d) in the field of Molecular etiology of bone sarcomas

The St. Anna Children’s Cancer Research Institute (CCRI)

Job Overview

St. Anna Kinderkrebsforschung CCRI - Children`s Cancer Researche Institute

Postdoc (m/f/d) in the field of Molecular etiology of bone sarcomas

Location:
Vienna

Research group:
Molecular Biology of Solid Tumors

Working hours:
Full-time

Exact knowledge of tumor etiology is required to design models for efficient preclinical testing and personalization of cancer therapies. However, tissue and developmental stage of origin remain an enigma for many childhood cancers severely hampering progress in pediatric cancer research and treatment.

Funded by an international organization, St. Anna Children´s Cancer Research Institute (CCRI) has joined forces with the Medical University of Vienna (MUW) and the University of Natural Resources and Life Sciences (BOKU) to track the origins of pediatric bone sarcomas using developmental and trans-species genomics. The interdisciplinary consortium is located in Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences.

We are looking for a molecular biologist at post-doctoral level who wants to contribute to solving one of the most mysterious puzzles in pediatric oncology by employing a broad spectrum of (single-cell) genomic and functional analyses at the interface of developmental and cancer biology.

As a Postdoc, you will

  • Join the Molecular Biology of Solid Tumors group at CCRI, led by Heinrich Kovar
  • Be part of and contribute to the coordination of a strong, well-funded, multidisciplinary consortium
  • Get involved in a highly cooperative and ambitious research project across three research institutions in Vienna
  • Plan and perform genetic perturbation experiments in primary cells in vitro and in vivo, and analyze functional consequences using cutting-edge molecular technologies
  • Apply a broad spectrum of cell biology, molecular biology, and omics methods
  • Bring in your own ideas and expertise to make the project your own
  • Interpret, present, and discuss your results with biologists and clinical researchers locally and internationally
  • Independently monitor the literature and community resources to keep abreast with latest developments and to identify information, data, and methods to integrate in your own work
  • Write papers, visit conferences, review papers, apply for fellowships, and contribute to grants
  • Contribute to the supervision of junior group members

Your Profile

  • PhD in a relevant life sciences subject (molecular biology, biotechnology, genomics, pharmacy, etc.)
  • At least one year of postdoctoral experience
  • At least two first-author publications in reputable journals
  • Good knowledge of and prior experience in cancer biology and/or developmental biology
  • Extensive experience with state-of-the-art cell culture, molecular biology, gene editing and omics technologies
  • Experience with bulk and/or single cell genomic/epigenomic technologies is desirable
  • Excellent verbal and written communication skills in English (German not required)
  • An exceptional level of enthusiasm, determination, and creativity

Our Offer

  • A four-years-contract for a challenging position in a meaningful, inspiring, and international environment
  • An outstanding working atmosphere in a strong team with excellent research and development opportunities
  • Access to state-of-the-art infrastructure
  • Flexible working hours, discounted lunch in our canteen and other great benefits
  • Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life
  • A fair and attractive salary package according to the Austrian Science Fund FWF (https://www.fwf.ac.at/en/research-funding/personnel-costs/)

Who we are

The St. Anna Children’s Cancer Research Institute (CCRI), located in the center of Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences, is an international and multidisciplinary competence center striving to improve treatment of children and adolescents with cancer by connecting translational and clinical research with open-minded exploration of basic disease mechanisms. Through close cooperation between clinic and research, the CCRI provides an ideal environment for cutting-edge research and its translation into clinical practice. To achieve our ultimate goal of advancing the well-being of patients, the CCRI constantly pushes scientific boundaries and strongly promotes close collaboration and exchange with external institutions like the Medical University of Vienna, the Technical University and the University of Natural Resources and Life Sciences, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) and the Institute of Molecular Pathology (IMP).

The Molecular Biology of Solid Tumors Group at CCRI performs predominantly basic research with the aim of translating clinical observations into molecular patterns, and molecular patterns into diagnostic/prognostic tools and novel treatment options. Since many years, we have been focusing on understanding the molecular etiology of pediatric bone sarcomas. There is an urgent need for new treatment options for these very malignant cancers in children and adolescents. The ultimate goal of our research is the development of novel disease models that allow for preclinical testing and optimization of innovative therapies.

The CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to race, color, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances.

Find more information here: https://science.ccri.at/ und https://kinderkrebsforschung.at/.

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